| Name | Year | Ratio to MLB average | Ratio to MLB second best |
|---|---|---|---|
| Randy Johnson | 2001 | 2.01 | 1.20 |
| Dazzy Vance |
1924 |
2.83 |
1.49 |
| Dazzy Vance |
1925 |
2.77 |
1.42 |
| Cy Seymour |
1898 |
2.63 |
1.30 |
| Rube Waddell |
1900 |
2.37 |
1.43 |
| Rube Waddell | 1903 |
2.36 |
1.28 |
| Rube Waddell | 1902 |
2.36 |
1.26 |
| Bob Feller |
1938 |
2.28 |
1.26 |
| Dazzy Vance |
1923 |
2.22 |
1.33 |
| Herb Score |
1955 |
2.21 |
1.27 |
| Rube Waddell |
1904 |
2.19 |
1.25 |
| Johnny Vandermeer |
1942 |
2.02 |
1.32 |
| Nolan Ryan |
1973 |
2.02 |
1.36 |
| Nolan Ryan |
1989 |
2.02 |
1.34 |
| Bob Feller |
1940 |
2.00 |
1.21 |
| Bob Feller |
1939 |
2.16 |
1.26 |
| Rube Waddell |
1907 |
2.05 |
1.30 |